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Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury.

Wenjun ZhangSimon J ConwayYing LiuPaige SniderHanying ChenHongyu GaoYunlong LiuKadir IsidanKevin J LopezGonzalo CampanaPing LiBurcin EkserHeather FrancisWeinian ShouChandrashekhar Kubal
Published in: Cells (2021)
Collectively, our scRNA-seq data provided insight into the landscape of activated HSC populations and the dynamic transitional pathway from HSC to myofibroblasts in response to liver injury.
Keyphrases
  • liver injury
  • single cell
  • drug induced
  • rna seq
  • induced apoptosis
  • high throughput
  • cell cycle arrest
  • big data
  • oxidative stress
  • gene expression
  • dna methylation
  • machine learning
  • deep learning