Igniting the flame in arthritis: C5aR2 controls endothelial transcytosis of C5a.

Published in: Science immunology (2020)

C5aR2 transports C5a generated in the arthritic joint to the blood vessel endothelium as the first step in C5aR1-driven neutrophil arrest and crawling.

Keyphrases

blood brain barrier
rheumatoid arthritis
nitric oxide
endothelial cells
gas chromatography
high resolution
tandem mass spectrometry
liquid chromatography