The BioDoseNet image repository used as a training tool for the dicentric assay.
Omar García LimaAna Rada-TarifaErika Lafuente-ÁlvarezJorge Ernesto González MesaTania MandinaGabriela Muñoz-VelasteguiYanara Astudillo-SilvaNorma MonjagataSara Aguilar-CoronelAida Falcón de VargasPublished in: International journal of radiation biology (2019)
Purpose: This paper describes how the BioDoseNet image repository was used as a training tool for the dicentric assay.Materials and methods: The training was implemented in three phases: introduction to dicentric scoring, dose response curve elaboration and dose assessment exercise. Four labs without previous experience in the dicentric assay participated and four modules of the repository were used.Results: The labs become familiar with aberrations induced by ionizing radiation. The labs were able to generate data for the elaboration of a dose response curve and then successfully estimated doses and irradiated fractions in six blind samples.Conclusions: The performance of these laboratories during the exercise demonstrates the efficacy of the BioDoseNet image repository as a training tool and the utility of web based scoring for the dicentric assay community.