Protective effect of bioactive components from Rubi fructus against oxidative damage in human ovarian granulosa cells induced by 2,2-azobis (2-methylpropionamidine) dihydrochloride.

Yulin ZhangXusheng LiRuijing LiuXin HuangYiting YangJingquan YuanYing ZhangJianxia SunWeibin Bai

Published in: Journal of the science of food and agriculture (2024)

Isoquercitrin, a bioactive component in R. fructus, has a significant protective effect on oxidative damage induced by 2,2-azobis (2-methylpropionamidine) dihydrochloride in human ovarian granulosa cells, providing evidence for its potential application in protecting ovarian function. © 2024 Society of Chemical Industry.

Keyphrases

induced apoptosis
endothelial cells
cell cycle arrest
induced pluripotent stem cells
polycystic ovary syndrome
endoplasmic reticulum stress
type diabetes
cell death
oxidative stress