Haemodynamic phenotypes and survival in patients with systemic sclerosis: the impact of the new definition of pulmonary arterial hypertension.
Panagiota XanthouliSuzana JordanNicklas MildeAlberto MarraNorbert BlankBenjamin EgenlaufMatthias GorenfloSatenik HarutyunovaHanns-Martin LorenzChristian NagelVivienne TheobaldMona LichtblauCharlotte BerlierSilvia UlrichEkkehard GrünigNicola BenjaminOliver DistlerPublished in: Annals of the rheumatic diseases (2019)
The data of this study show that a PVR threshold ≥3 WU is too high to enable an early diagnosis of PAH. A PVR threshold ≥2 WU was already associated with pulmonary vascular disease, significantly reduced survival and would be more appropriate in SSc patients with mild PAH.
Keyphrases
- systemic sclerosis
- pulmonary arterial hypertension
- pulmonary hypertension
- interstitial lung disease
- pulmonary artery
- free survival
- polycyclic aromatic hydrocarbons
- electronic health record
- big data
- rheumatoid arthritis
- coronary artery
- deep learning
- idiopathic pulmonary fibrosis
- data analysis
- artificial intelligence