Insulin, but Not Metformin, Supports Wound Healing Process in Rats with Streptozotocin-Induced Diabetes.

Mateusz Mieczkowski Beata Mrozikiewicz-RakowskaTomasz SiwkoMagdalena Bujalska-ZadrożnyAnna de Corde-SkurskaRenata WolinskaEmilia GasinskaTomasz Grzela Piotr Foltynski Michal KowaraZofia MieczkowskaLeszek Czupryniak

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)

These results suggest that an insulin-based treatment is more beneficial than metformin, in terms of accelerating the wound healing process in an animal model of streptozocin-induced diabetes.

Keyphrases

type diabetes
diabetic rats
wound healing
glycemic control
high glucose
cardiovascular disease
oxidative stress
drug induced
high fat diet
endothelial cells
metabolic syndrome
adipose tissue
insulin resistance
combination therapy