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Associations Between Buprenorphine\Naloxone and Methadone Treatment and non-Opioid Substance Use in Prescription-Type Opioid Use Disorder: Secondary Analyses From the OPTIMA Study.

Hamzah BakouniHeidar SharafiSarah DrouinRaphaelle FortinStéphanie MarsanSuzanne BrissetteMaria Eugenia SociasBernard Le FollRon LimDidier Jutras-Aswad
Published in: Canadian journal of psychiatry. Revue canadienne de psychiatrie (2023)
Methadone did not show a significant effect on overall non-opioid substance use in POUD compared to BUP/NX treatment but was associated with lower odds of benzodiazepine and THC use in particular. Non-opioid substance use did not predict OAT outcomes. Further research is needed to ascertain whether specific patterns of polysubstance use (quantity and frequency) may affect treatment outcomes.
Keyphrases
  • chronic pain
  • pain management
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