There is a lack of evidence-based treatments of LA dysfunction in both primary and secondary stroke prevention. This is partly due to the lack of a practical clinical definition and unanswered questions concerning the clinical implications of LA dysfunction in patients without AF. Until such questions are resolved, addressing well-known cardiovascular risk factors, like hypertension and obesity, should be prioritized for preventing AF and ischemic stroke. These risk factors are closely tied to atrial remodeling, emphasizing the importance of targeting primary modifiable factors for preventing future morbidity and mortality.
Keyphrases
- atrial fibrillation
- left atrial
- cardiovascular risk factors
- catheter ablation
- risk factors
- end stage renal disease
- metabolic syndrome
- heart failure
- oxidative stress
- blood pressure
- newly diagnosed
- cardiovascular disease
- ejection fraction
- type diabetes
- prognostic factors
- chronic kidney disease
- insulin resistance
- weight loss
- mitral valve
- left ventricular
- current status
- blood brain barrier
- brain injury
- cerebral ischemia