Recurrent USP6 rearrangement in a subset of atypical myofibroblastic tumours of the soft tissues: low-grade myofibroblastic sarcoma or atypical/malignant nodular fasciitis?

Giorgia ArcovitoStefania CrucittaMarzia Del ReChiara CaporaliniAnnarita PalombaFilippo NozzoliAlessandro Franchi

Published in: Histopathology (2024)

Our findings support the notion that among soft-tissue neoplasms with fibroblastic/myofibroblastic phenotype, USP6 rearrangement is not limited to benign tumours, and warrants further investigation of genetic changes in myofibroblastic sarcomas.

Keyphrases

low grade
high grade
soft tissue
gene expression
genome wide
copy number