Sodium butyrate alleviates experimental autoimmune prostatitis by inhibiting oxidative stress and NLRP3 inflammasome activation via the Nrf2/HO-1 pathway.

Xiaoliang Hua Jiong ZhangJuan ChenRui FengLi ZhangXianguo ChenQing JiangCheng YangChao-Zhao Liang

Published in: The Prostate (2024)

NaB treatment can alleviates prostatic inflammation and pelvic pain associated with EAP by inhibiting oxidative stress and NLRP3 inflammasome activation via the Nrf2/HO-1 pathway. NaB has the potential as an effective agent in the treatment of EAP.

Keyphrases

oxidative stress
nlrp inflammasome
dna damage
ischemia reperfusion injury
signaling pathway
diabetic rats
chronic pain
advanced non small cell lung cancer
mouse model
rectal cancer
cell proliferation
spinal cord injury
pi k akt
combination therapy
endoplasmic reticulum stress
replacement therapy
heat shock protein