M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway.

Jie YaoZefen WangYong ChengChao MaYahua ZhongYilei XiaoXu GaoZhi-Qiang Li

Published in: Journal of translational medicine (2021)

Collectively, these findings indicate that M2 macrophage-derived exosomal miR-15a and miR-92a inhibit cell migration and invasion of glioma cells through PI3K/AKT/mTOR signaling pathway.

Keyphrases

signaling pathway
cell proliferation
long non coding rna
single cell
pi k akt
long noncoding rna
cell therapy
epithelial mesenchymal transition
high grade
stem cells
endoplasmic reticulum stress