Bisphosphonates attenuate age-related muscle decline in Caenorhabditis elegans.

Luke SladeShelby E BollenJoseph J BassBethan E PhillipsKenneth SmithDaniel J WilkinsonNathaniel J SzewczykPhilip J AthertonTimothy Etheridge

Published in: Journal of cachexia, sarcopenia and muscle (2023)

Despite lacking an endoskeleton, ZA delays Caenorhabditis elegans sarcopenia, which translates to improved neuromuscular function across the life course. Bisphosphonates might, therefore, be an immediately exploitable anti-sarcopenia therapy.

Keyphrases

skeletal muscle
community dwelling
stem cells
bone marrow
smoking cessation
chemotherapy induced