Beyond Early LDL Cholesterol Lowering to Prevent Coronary Atherosclerosis in Familial Hypercholesterolemia.
Shirin IbrahimLaurens F ReeskampJim N de GoeijG Kees HovinghR Nils PlankenWillem A BaxJames K MinJames P EarlsPaul KnaapenAlbert WiegmanErik S G StroesNick S NurmohamedPublished in: European journal of preventive cardiology (2024)
Lifetime exposure to LDL-C determines coronary plaque burden in FH, underlining the need of early as well as potent treatment initiation. Periodic CCTA may offer a unique opportunity to monitor coronary atherosclerosis and personalize treatment in FH.