Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study.
Nader Ali IsmailEman Ali ToraihHatem Mohamed AmeenAmal Hussein Ahmed GomaaRadwa El-Sayed Mahmoud MariePublished in: Immunological investigations (2020)
Individuals with homozygosity of rs231775 CTLA4 variant represented AA disease risk and increased severity than their counterparts.Abbreviations: AA: Alopecia areata; CTLA4: Cytotoxic T-lymphocyte Associated Protein 4; SNP: Single nucleotide polymorphism; LADA: Latent autoimmune diabetes in adults; SLE: Systemic lupus erythematosus; SCU: Suez Canal University; SALT: Severity of Alopecia Tool; DNA: Deoxyribonucleic acid; RT-PCR: Real-time polymerase chain reaction, HWE: Hardy-Weinberg equation; RA: rheumatoid arthritis.
Keyphrases
- systemic lupus erythematosus
- disease activity
- rheumatoid arthritis
- genome wide
- ankylosing spondylitis
- type diabetes
- cardiovascular disease
- peripheral blood
- multiple sclerosis
- circulating tumor
- glycemic control
- dna methylation
- gene expression
- single molecule
- cell free
- copy number
- insulin resistance
- weight loss
- high density
- circulating tumor cells