Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes.
Konstantinos TheofilatosStefan StojkovicMaria HasmanSander W van der LaanFerheen BaigJavier Barallobre-BarreiroLukas Emanuel SchmidtSiqi YinXiaoke YinSean A BurnapBhawana SinghJude PophamOlesya HarkotStephanie KampfMaja Carina NackenhorstAndreas StrasslChristian LoeweSvitlana DemyanetsChristoph NeumayerMartin BilbanChristian HengstenbergKurt HuberGerard PasterkampJohann WojtaManuel MayrPublished in: Circulation research (2023)
Plaque proteomics redefined clinically relevant patient groups with distinct outcomes, identifying subgroups of male and female patients with elevated risk of future cardiovascular events.