Changes in the tumor oxygenation but not in the tumor volume and tumor vascularization reflect early response of breast cancer to neoadjuvant chemotherapy.

Mikhail V PavlovAnna P BavrinaVladimir I PlekhanovGerman Yu GolubyatnikovAnna G OrlovaPavel V SubochevDiana A DavydovaIlya V TurchinAnna V Maslennikova

Published in: Breast cancer research : BCR (2023)

Diffuse optical spectroscopy imaging appeared to be a robust tool for early predicting breast cancer response to chemotherapy. It may help identify patients who need additional molecular genetic study of the tumor in order to find the source of resistance to treatment, as well as to correct the treatment regimen.

Keyphrases

neoadjuvant chemotherapy
high resolution
locally advanced
lymph node
single molecule
gene expression
radiation therapy
genome wide
mass spectrometry
low grade
copy number
blood flow