Ligand-mediated nanomedicines against breast cancer: a review.

Guilherme F PichethFernando A de O GanzellaJoão Oc FilizzolaYan K CanquerinoGabriela C CardosoMichelle B ColliniLeonardo B ColautoMaria Cristina Figueroa-MagalhãesEdneia Asr CavalieriGiseli Klassen

Published in: Nanomedicine (London, England) (2022)

Ligand-mediated targeting represents the cutting edge in precision-guided therapy for several diseases. Surface engineering of nanomedicines with ligands exhibiting selective or tailored affinity for overexpressed biomolecules of a specific disease may increase therapeutic efficiency and reduce side effects and recurrence. This review focuses on newly developed approaches and strategies to improve treatment and overcome the mechanisms associated with breast cancer resistance.

Keyphrases

smoking cessation
free survival
drug delivery
breast cancer risk
combination therapy