Early Left Ventricular Systolic Dysfunction Detected by Two-Dimensional Speckle-Tracking Echocardiography in Young Patients with Congenital Generalized Lipodystrophy.
Christiane Bezerra Rocha LiberatoNatália Bitar da Cunha OlegarioVirginia Oliveira FernandesAna Paula Dias Rangel MontenegroGrayce Ellen da Cruz Paiva LimaLívia Aline de Araújo BatistaLívia Vasconcelos MartinsJaquellyne Gurgel Penaforte-SaboiaIvan Lucas Rocha LiberatoLarissa Ferreira LopesCatarina Brasil d'AlvaFrederico Luís Braz FurtadoRicardo Luiz De Medeiros LimaLucia Helena Coelho NóbregaJosivan Gomes LimaRenan Magalhães Montenegro Júniornull nullPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)
The 2D-STE revealed precocious left ventricular systolic dysfunction in a young CGL population with normal systolic function by ECHO. Early exposure to common metabolic abnormalities as insulin resistance, hyperglycemia, and hypoleptinemia must be involved in myocardial damage in these patients.
Keyphrases
- left ventricular
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- acute myocardial infarction
- aortic stenosis
- insulin resistance
- mitral valve
- oxidative stress
- left atrial
- end stage renal disease
- newly diagnosed
- blood pressure
- magnetic resonance
- adipose tissue
- middle aged
- type diabetes
- metabolic syndrome
- prognostic factors
- magnetic resonance imaging
- patient reported outcomes
- skeletal muscle
- polycystic ovary syndrome
- patient reported
- diffusion weighted imaging