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TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis.

Yun YangXiu-Ming LiJing-Ru WangYan LiWen-Long YeYi WangYu-Xuan LiuZhi-Yong DengWen-Juan GanHua Wu
Published in: Journal of inflammation (London, England) (2022)
These in vivo data demonstrate that TRIP6 serves as a positive regulator of DSS-induced colitis through interactions with TRAF6 resulting in the activation of inflammatory TRAF6 signaling, highlighting its therapeutic promise as a protein that theoretically can be targeted to prevent or treat colitis.
Keyphrases
  • oxidative stress
  • big data
  • electronic health record
  • cancer therapy
  • machine learning
  • drug delivery
  • protein protein
  • artificial intelligence
  • ulcerative colitis