Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells.

Hoda El-KehdyMehdi NajarJoery De KockDouaa Moussa AghaVera RogiersMakram MerimiLaurence LagneauxEtienne M SokalMustapha Najimi

Published in: Cells (2020)

These results indicate that ADHLSCs are highly sensitive to inflammation and respond to such signals by adjusting their gene and protein expression. Accordingly, monitoring the inflammatory status of patients at the time of cell transplantation, will certainly help in enhancing ADHLSC safety and efficiency.

Keyphrases

oxidative stress
cell therapy
single cell
genome wide
copy number
gene expression
dna methylation
bone marrow
high resolution
childhood cancer
tandem mass spectrometry