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The prognostic value of the Merkel cell polyomavirus serum antibody test: A dual institutional observational study.

David Michael MillerSophia Z ShalhoutKayla M WrightMatt A MillerHoward L KaufmanKevin S EmerickHarrison T ReederAnn W SilkManisha Thakuria
Published in: Cancer (2024)
Merkel cell carcinoma (MCC) is a potentially aggressive skin cancer, and tools to predict patient outcomes are limited. A blood test called anti-Merkel cell panel (AMERK), which checks for specific antibodies related to this cancer, might give us some clues. In this study, we looked at 261 MCC patients who took the AMERK test within 90 days of diagnosis. We found that patients with an initial positive AMERK result tended to have better outcomes, especially if their cancer was in the early stages. However, it is important to note that this study has limitations, including using retrospective data and exploratory analyses.
Keyphrases
  • papillary thyroid
  • single cell
  • skin cancer
  • cell therapy
  • squamous cell
  • type diabetes
  • squamous cell carcinoma
  • machine learning
  • electronic health record
  • mesenchymal stem cells
  • bone marrow
  • adipose tissue