Maternal L-carnitine supplementation ameliorates renal underdevelopment and epigenetic changes in male mice offspring due to maternal smoking.

Stefanie StangenbergLong The NguyenYik Lung ChanAmgad ZakyCarol A PollockHui ChenSonia Saad

Published in: Clinical and experimental pharmacology & physiology (2018)

The effect of maternal SE on renal underdevelopment involves global epigenetic alterations from birth, which can be prevented by maternal LC supplementation.

Keyphrases

birth weight
pregnancy outcomes
dna methylation
gestational age
gene expression
type diabetes
metabolic syndrome
smoking cessation
mouse model
skeletal muscle
insulin resistance
simultaneous determination
preterm birth