Strain Echocardiography to Predict Postoperative Atrial Fibrillation.
Francisco Javier SánchezEsther PueyoEmiliano Raúl DiezPublished in: International journal of molecular sciences (2022)
Postoperative atrial fibrillation (POAF) complicates 15% to 40% of cardiovascular surgeries. Its incidence progressively increases with aging, reaching 50% in octogenarians. This arrhythmia is usually transient but it increases the risk of embolic stroke, prolonged hospital stay, and cardiovascular mortality. Though many pathophysiological mechanisms are known, POAF prediction is still a hot topic of discussion. Doppler echocardiogram and, lately, strain echocardiography have shown significant capacity to predict POAF. Alterations in oxidative stress, calcium handling, mitochondrial dysfunction, inflammation, fibrosis, and tissue aging are among the mechanisms that predispose patients to the perfect "atrial storm". Manifestations of these mechanisms have been related to enlarged atria and impaired function, which can be detected prior to surgery. Specific alterations in the atrial reservoir and pump function, as well as atrial dyssynchrony determined by echocardiographic atrial strain, can predict POAF and help to shed light on which patients could benefit from preventive therapy.
Keyphrases
- atrial fibrillation
- left atrial
- catheter ablation
- oxidative stress
- end stage renal disease
- left ventricular
- ejection fraction
- newly diagnosed
- chronic kidney disease
- oral anticoagulants
- left atrial appendage
- direct oral anticoagulants
- heart failure
- risk factors
- minimally invasive
- pulmonary hypertension
- prognostic factors
- percutaneous coronary intervention
- type diabetes
- patients undergoing
- peritoneal dialysis
- acute coronary syndrome
- dna damage
- stem cells
- bone marrow
- blood brain barrier
- coronary artery disease
- cell therapy
- cardiovascular disease
- drug induced
- ischemia reperfusion injury
- patient reported
- blood flow
- liver fibrosis
- water quality
- cardiac resynchronization therapy
- electronic health record
- replacement therapy