Advances towards Cell-Specific Gene Transfection: A Small-Molecule Approach Allows Order-of-Magnitude Selectivity.

Thies DirksmeyerPaul Stahl Cecilia Vallet Shirley K Knauer Michael Giese Carsten Schmuck Christoph Hirschhäuser

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2022)

Invited for the cover of this issue are Christoph Hirschhäuser and his colleagues from the University of Duisburg-Essen. The image depicts a biotin-labelled transfection vector selectively channelling DNA into a cancer cell. The QR code on the label will lead you to a video abstract (https://youtu.be/OgXfBPZTKGA). Read the full text of the article at 10.1002/chem.202104618.

Keyphrases

small molecule
single molecule
single cell
circulating tumor
deep learning
cell therapy
genome wide
copy number
cell free
protein protein
smoking cessation
stem cells
genome wide identification
dna methylation
machine learning
bone marrow
structural basis
transcription factor
genome wide analysis