TRPV1-mediated sonogenetic neuromodulation of motor cortex in freely moving mice.
Kevin XuYaoheng YangZhongtao HuYimei YueYan GongJianmin CuiJoseph P CulverMichael R BruchasHong Chen
Published in: Journal of neural engineering (2023)
TRPV1-mediated sonogenetics can achieve effective and safe neuromodulation at the cortex with carefully selected FUS parameters. These findings expand the application of this technique to include superficial brain targets.