Analytical performance of the endogenous thrombin potential-based activated protein C resistance assay on the automated ST Genesia system.

Laure MorimontCharline LeclercqMarie DidembourgÉmilie De GottalAudrey CarloUlysse GaspardJean-Michel DognéJonathan Douxfils

Published in: Research and practice in thrombosis and haemostasis (2022)

This study is the first reporting the analytical performances of the ETP-based APC resistance assay on an automated platform. Results support the concept that this test, when incorporated into clinical routine, could become a promising regulatory and clinical tool to document on the thrombogenicity of female hormonal therapies.

Keyphrases

high throughput
machine learning
deep learning
liquid chromatography
emergency department
risk assessment
adipose tissue
polycystic ovary syndrome
binding protein
amino acid
mass spectrometry
human health
adverse drug