This study suggested that MRI SVZ involvement at diagnosis is an independent risk factor for overall survival and progression-free survival in IDH wild-type glioblastoma patients. Based on MR imaging, we also found that SVZ contacting glioblastomas had a larger proportion of crossing midline tumors and multifocal lesions. In addition, patients with SVZ contact in our research presented a lower proportion of MGMT promoter methylation.
Keyphrases
- wild type
- free survival
- dna methylation
- contrast enhanced
- end stage renal disease
- gene expression
- ejection fraction
- genome wide
- magnetic resonance imaging
- newly diagnosed
- transcription factor
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- magnetic resonance
- computed tomography
- diffusion weighted imaging
- high grade
- patient reported