Prediction of gestational age based on genome-wide differentially methylated regions.
Jon BohlinS E HåbergP MagnusS E ReeseH K GjessingM C MagnusC L ParrC M PageS J LondonW NystadPublished in: Genome biology (2016)
DNA methylation at birth appears to be a good predictor of gestational age. Ultrasound gestational age is more strongly associated with methylation than last menstrual period gestational age. The CpGs linked with our gestational age prediction model, and their associated genes, differed substantially from the corresponding CpGs and genes associated with a chronological age prediction model.