Mesenchymal stem cells cultured in serum-free medium ameliorate experimental peritoneal fibrosis.

Kohei NagasakiAyumu NakashimaRyo TamuraNaoki IshiuchiKiyomasa HondaToshinori UenoShigehiro DoiYukio KatoTakao Masaki

Published in: Stem cell research & therapy (2021)

Serum-free culture conditions can enhance the antifibrotic abilities of MSCs by suppressing inflammation. Administering ex vivo expanded SF-MSCs may be a potential therapy for preventing peritoneal fibrotic progression.

Keyphrases

mesenchymal stem cells
umbilical cord
bone marrow
oxidative stress
cell therapy
endothelial cells
systemic sclerosis
human health