Safety of Immune Checkpoint Inhibitors in Patients With Advanced Chronic Kidney Disease: A Retrospective Cohort Study.

Bruce C Tiu Ian A StrohbehnSophia ZhaoTianqi OuyangPaul HannaQiyu WangShruti GuptaDavid E LeafKerry L ReynoldsMeghan E Sise

Published in: The oncologist (2023)

ICIs are not associated with increased risk of AKI or new-onset kidney failure compared with other antineoplastic therapies in patients with advanced CKD. Advanced CKD did not increase the risk of extra-renal irAEs, although these patients suffered from lower overall survival.

Keyphrases

chronic kidney disease
end stage renal disease
peritoneal dialysis
ejection fraction
newly diagnosed
prognostic factors
patient reported outcomes