Tapentadol for the Treatment of Moderate-to-Severe Acute Pain in Children Under the Age of Two Years.

Ayman EissaEva TarauChristoph Beuter Tatjana Radic Estelle WatsonMelanie SohnsClaudia Lefeber Gregory B Hammer

Published in: Journal of pain research (2021)

Tapentadol showed a favorable PK and safety profile in children <2 years of age. Multiple tapentadol OS dosing is efficacious and generally well tolerated in children ≥2 years and might also be a useful treatment option for children <2 years in need of strong analgesics.

Keyphrases

young adults
chronic pain
high intensity
smoking cessation
replacement therapy