Endoplasmic Reticulum (ER) Stress in Part Mediates Effects of Angiotensin II in Pancreatic Beta Cells.

Latha RamalingamBoontharick SopontammarakKalhara R MenikdiwelaNaima Moustaid-Moussa

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)

This research provides new mechanistic insight into the role of RAAS activation via ER stress on beta cell dysfunction and provides additional evidence for protective effects of RAAS inhibition in T2D.

Keyphrases

angiotensin ii
endoplasmic reticulum
induced apoptosis
angiotensin converting enzyme
vascular smooth muscle cells
cell cycle arrest
single cell
oxidative stress
cell therapy
endoplasmic reticulum stress
cell death
mesenchymal stem cells
cell proliferation