Roles of alpha-7 nicotinic acetylcholine receptors and spleen in the lung injury induced by a repeated saline lavage in rat.

Hossein Fatemikia Amir Reza Dehghanian Bizhan Ziaian Maryam Farokhipour Farzaneh Ketabchi

Published in: BMC pulmonary medicine (2022)

In this study, we indicated that α7nAChR and spleen play roles in cholinergic anti-inflammatory pathways in saline lavage-induced lung injury. However, our results are in favor of at least some direct effects of α 7nAChR in the lung.

Keyphrases

anti inflammatory
high glucose
oxidative stress