Osteoporosis in a murine model of postmenopausal lupus.
Jauquline NordqvistM K LagerquistL GrahnemoA KoskelaU IslanderH CarlstenPublished in: Lupus (2019)
Ovariectomized MRL/lpr mice constitute a valuable experimental model for studies of osteoporosis development in postmenopausal systemic lupus erythematosus and this model is thus suitable for future studies of osteoporosis treatment in systemic lupus erythematosus.
Keyphrases
- bone mineral density
- systemic lupus erythematosus
- postmenopausal women
- body composition
- disease activity
- case control
- rheumatoid arthritis
- current status
- high fat diet induced
- type diabetes
- metabolic syndrome
- skeletal muscle
- combination therapy
- replacement therapy
- insulin resistance
- bone loss
- adipose tissue
- wild type