PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth.
Nathalie MagneVéronique RousseauKévin DuarteSandrine Poëa-GuyonVincent GleizeAlexandre MutelCharlotte SchmittHélène CastelAhmed IdbaihEmmanuelle HuillardMarc SansonJean-Vianney BarnierPublished in: Cellular oncology (Dordrecht) (2021)
Our results indicate that PAK3 plays a unique role among PAKs in glioma development and may represent a potential therapeutic target.