Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia.

Marco MøllerSimon FredholmMathias E JensenGitta Wörtwein Julie R Larsen Tina Vilsbøll Niels Odum Anders Fink-Jensen

Published in: CNS spectrums (2020)

Prediabetic vs NGT patients with schizophrenia treated with clozapine or olanzapine had increased serum levels of several proinflammatory cytokines, further substantiating the link between inflammation and T2D. Treatment with liraglutide did not affect the investigated cytokines. Further testing of these findings in larger numbers of individuals is needed.

Keyphrases

oxidative stress
atomic force microscopy
combination therapy
replacement therapy
smoking cessation
chemotherapy induced