Late toxicity of image-guided hypofractionated radiotherapy for prostate: non-randomized comparison with conventional fractionation.
Barbara Alicja Jereczek-FossaAlessia SurgoPatrick MaisonneuveAndrea MaucieriMarianna Alessandra GerardiDario ZeriniGiulia MarvasoDelia CiardoStefania VolpeDamaris Patricia RojasGiulia RivaOmbretta AlessandroSamantha DicuonzoGiuseppe FanettiPaola RomanelliAnna StarzyńskaFederica CattaniRaffaella CambriaCristiana FodorCristina GaribaldiChiara RomanòOttavio De CobelliRoberto OrecchiaPublished in: La Radiologia medica (2018)
A small increase in mild late toxicity, but not statistically significant increase in severe late toxicity in the hypo-IGRT group when compared with conventional non-IGRT group was observed. Our study confirmed that IGRT allows for safe moderate hypofractionation, offering a shorter overall treatment time, a good impact in terms of RFS and providing potentially more economic health care.