Plasma circulating miR-23~27~24 clusters correlate with the immunometabolic derangement and predict C-peptide loss in children with type 1 diabetes.
Silvia GaravelliSara BruzzanitiElena TagliabueDario Di SilvestreFrancesco PrattichizzoEnza MozzilloValentina FattorussoLucia La SalaAntonio CerielloAnnibale A PucaPierluigi MauriRocky StrolloMarco MariglianoClaudio MaffeisAlessandra PetrelliEmanuele BosiAdriana FranzeseMario GalganiGiuseppe MataresePaola de CandiaPublished in: Diabetologia (2020)
We have pinpointed a novel miR-23a-3p/miR-23b-3p/miR-24-3p/miR-27b-3p/OPG plasma signature that may be developed into a novel blood-based method to better stratify patients with type 1 diabetes and predict C-peptide loss.