The current state of the art of plasmonic nanofibrous mats as SERS substrates: design, fabrication and sensor applications.
Sangeeta YadavJitendra SatijaPublished in: Journal of materials chemistry. B (2021)
Surface-enhanced Raman scattering (SERS) is a widely used analytical tool that allows molecular fingerprint-based ultra-sensitive detection through an enhanced electromagnetic field generated by plasmonic metal nanoparticles (MNPs) by virtue of their localized surface plasmon resonance (LSPR). Although significant progress has been made in the design and fabrication of a variety of SERS substrates, MNP-decorated electrospun nanofibrous (NF) mats have attracted much attention due to their unique nanoscale structural and functional properties. This review focuses on the current state of the art in the fabrication of plasmonic NF mats with the main focus on the pre-mix, in situ, and ex situ approaches. The characteristic functional advantages and limitations of these strategies are also highlighted, which might be helpful for the research community when adopting a suitable approach. The potential of these plasmonic NF mats as a SERS-active optical sensor substrate, and their performance parameters such as the limit of detection, analytical range, and enhancement factor, and real-world applications are also discussed. The summary and futuristic discussion in this review might be of significant value in developing plasmonic NF mat-based SERS-active point-of-care diagnostic chips for a wide range of applications.
Keyphrases
- sensitive detection
- label free
- quantum dots
- signaling pathway
- single molecule
- tissue engineering
- lps induced
- loop mediated isothermal amplification
- energy transfer
- pi k akt
- gold nanoparticles
- nuclear factor
- oxidative stress
- raman spectroscopy
- high resolution
- mental health
- inflammatory response
- atomic force microscopy
- low cost
- reduced graphene oxide
- working memory
- visible light
- mass spectrometry
- high speed
- immune response
- cell proliferation