Is serotonin transporter brain binding associated with the cortisol awakening response? An independent non-replication.

Juliane ConradiJonas E SvenssonSøren V Larsen Vibe G Frøkjær

Published in: PloS one (2023)

We could not confirm a positive association between CAR and prefrontal 5-HTT BPND in this independent dataset. Also, sex differences in the association were not apparent. Our data do not exclude that the serotonin transporter system is involved in the regulation of stress responses in at-risk or manifest depressed states.

Keyphrases

functional connectivity
resting state
working memory
electronic health record
white matter
transcranial magnetic stimulation
diffusion weighted imaging
dna binding
cerebral ischemia
multiple sclerosis
machine learning
transcription factor
deep learning
brain injury