Interleukin 1 alpha administration is neuroprotective and neuro-restorative following experimental ischemic stroke.
Kathleen E SalmeronMichael E ManiskasDanielle N EdwardsRaymond WongIvana RajkovicAmanda TroutAbir A RahmanSamantha HamiltonJustin F FraserEmmanuel PinteauxGregory Jaye BixPublished in: Journal of neuroinflammation (2019)
Taken together, our present study suggests for the first time that IL-1α could, unexpectedly, be an effective ischemic stroke therapy with a broad therapeutic window.