Cholinesterase inhibitors and non-steroidal anti-inflammatory drugs and the risk of peptic ulcers: A self-controlled study.

Máté Szilcz Jonas W Wastesson Amaia Calderon-Larranaga Daniel Prieto Alhambra Pierre-Olivier Blotière Géric Maura Kristina Johnell

Published in: Journal of the American Geriatrics Society (2023)

We found that the risk of peptic ulcer associated with the concomitant use of NSAIDs and ChEIs was over and beyond the risk associated with NSAIDs alone. Our results underscore the importance of carefully considering the risk of peptic ulcers when co-prescribing NSAIDs and ChEIs to adults aged 65 years and older.

Keyphrases

anti inflammatory drugs
primary care
wound healing
community dwelling
emergency department