Lower circulating endocannabinoid levels in children with autism spectrum disorder.

Adi AranMaya EylonMoria HarelLola PolianskiAlina NemirovskiSigal TepperAviad SchnappHanoch CassutoNadia WattadJoseph Tam

Published in: Molecular autism (2019)

We found lower serum levels of AEA, PEA, and OEA in children with ASD. Further studies are needed to determine whether circulating endocannabinoid levels can be used as stratification biomarkers that identify clinically significant subgroups within the autism spectrum and if they reflect lower endocannabinoid "tone" in the brain, as found in animal models of ASD.

Keyphrases

autism spectrum disorder
intellectual disability
attention deficit hyperactivity disorder
young adults
white matter
multiple sclerosis
subarachnoid hemorrhage
cerebral ischemia