Subjective cognitive concern in multiple sclerosis is associated with reduced thalamic and cortical gray matter volumes.
Isaiah KletenikEnrique AlvarezJustin M HonceBrooke ValdezTimothy L VollmerLuis D MedinaPublished in: Multiple sclerosis journal - experimental, translational and clinical (2019)
Subjective cognitive concern in MS is associated with reduced thalamic and cortical gray matter volumes, areas of the brain that have been implicated in objective cognitive impairment. These findings may lend neuroanatomical significance to subjective cognitive concerns and patient-reported outcomes as measured by Neuro-QoL.