Seroconversion following empiric praziquantel treatment as confirmatory diagnostic tool for chronic schistosomiasis.

We report on six patients with suspected chronic schistosomiasis and negative microbiological findings at baseline. All patients were treated empirically with praziquantel and all seroconverted 20 days to 2 months after treatment. We suggest that seroconversion after praziquantel treatment may be used to diagnose chronic schistosomiasis.