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Genomic and Transcriptomic Analysis of Colistin-Susceptible and Colistin-Resistant Isolates Identify Two-Component System EvgS/EvgA Associated with Colistin Resistance in Escherichia coli.

Fen WanLinna XuZhi RuanQixia Luo
Published in: Infection and drug resistance (2021)
This study demonstrated that PmrB L14R amino acid substitution resulted in colistin resistance, and two-component system EvgS/EvgA might participate in colistin resistance in E. coli.
Keyphrases
  • escherichia coli
  • klebsiella pneumoniae
  • acinetobacter baumannii
  • pseudomonas aeruginosa
  • multidrug resistant
  • gram negative
  • drug resistant
  • biofilm formation
  • amino acid
  • cystic fibrosis
  • copy number