Overexpression of TIGAR and HO-1 in peripheral blood mononuclear cells (PBMCs) of breast cancer patients treated with radiotherapy.

Aria Dianati-NasabHamid NasrollahiZahra KhoshdelMahboobeh GhorbaniSayed Mohammad Shafiee

Published in: International journal of radiation biology (2022)

The findings of this study showed that RT could overexpress TIGAR and HO-1 in PBMCs of breast cancer patients. More research is required to figure out the mechanisms behind the impacts of RT on increased catabolism and production of bilirubin or increased activity of TIGAR-related pathways and overexpression of TIGAR and HO-1.

Keyphrases

cell proliferation
pi k akt
transcription factor
early stage
radiation induced
signaling pathway
young adults