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Targeted quantification of N-1-(carboxymethyl) valine and N-1-(carboxyethyl) valine peptides of β-hemoglobin for better diagnostics in diabetes.

Mashanipalya G JagadeeshaprasadKedar B BatkulwarNishita N MeshramShalbha TiwariArvind M KorwarAmbika G UnnikrishnanMahesh J Kulkarni
Published in: Clinical proteomics (2016)
This study reports carboxymethylation as a predominant modification of N-1-β-valine of Hb, and quantification of CMV-β-Hb and CEV-β-Hb could be useful parameter for assessing the severity of diabetes.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • cancer therapy
  • metabolic syndrome
  • amino acid
  • red blood cell