Synthesis and Absolute Configuration of Habiterpenol.
Miyuki KonyaKenta ShimoyamaShiho ArimaTakashi FukudaRyuji UchidaHiroshi TomodaTohru NagamitsuPublished in: Organic letters (2020)
The synthesis of habiterpenol, a G2 checkpoint inhibitor, was achieved through the stereoselective Ti(III)-mediated radical cyclization of a β-epoxide as the key reaction. Moreover, the absolute configuration of habiterpenol was determined.
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