Ni(cod)(duroquinone)-Catalyzed C-N Cross-Coupling for the Synthesis of N , N -Diarylsulfonamides.

We report a C-N cross-coupling reaction of weakly nucleophilic N -arylsulfonamides and aryl bromides to access N , N -diarylsulfonamides using Ni(cod)(DQ) as a catalyst without additional ligands. The process is compatible with electron-deficient and electron-rich aryl and heteroaryl bromides (34 examples, 21-98%) and can be applied to the derivatization of an N -arylsulfonamide pharmaceutical compound.